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The tablet and oral solution dosage forms of citalopram hydrobromide are bioequivalent. Because citalopram is metabolized by multiple enzyme systems, inhibition of a single enzyme may not appreciably decrease citalopram clearance. Anyone considering the use of citalopram or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. In vitro and in vivo studies in animals suggest that citalopram is a highly selective serotonin reuptake inhibitor (SSRI) with minimal effects on norepinephrine (NE) and dopamine (DA) neuronal reuptake. Citalopram hydrobromide 40 mg capsules have an ivory body and a green cap and contain citalopram hydrobromide equivalent to 40 mg citalopram base.
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